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Conference 2018

October 9-12, 2018

Rachel Fogle

Assistant Professor of Biological Sciences
Integrative Sciences
Harrisburg University

As a broadly trained physiologist, my research interests are widespread. I am interested in biological systems under normal and pathological states, proteomics, and bioinformatics. My dissertation project involved the use of proteomics to detect sex-dependent differences in myocardial protein content following chronic alcohol abuse in a rat model. Specifically, I utilized chemical labeling technology (iTRAQ) to allow direct comparison between study groups. In conjunction with the proteomic studies, I utilized echocardiography to monitor changes in cardiac structure and function with increasing levels of alcohol consumption. This approach provided an excellent platform for correlating alterations in whole organ structure and function with alcohol-induced sub-cellular events.

One of my specific interests includes the field of quantitative proteomics and bioinformatics. Managing large datasets generated from proteome-based experiments has led to an appreciation for statistical tools that allow easier data analysis. As part of my graduate research, I developed a new statistical model using statistical software analysis packages, such as STATA and R, to allow combination of multiple datasets with related research hypotheses, thereby increasing the sample size for statistical analysis.

More recently, in addition to statistical modeling, I have broadened by research interests to include education research. Specifically, the implementation and validation of innovative team-based learning curriculum for responsible conduct of research (RCR). It is hypothesized that ethical decision-making abilities (both short-term and long-term) can be increased through the use of a team-based, interactive RCR curriculum that is malleable to the instructor, biomedical discipline, and targeted audience.


(A3): Research Ethics & Scientific Integrity
10 October 2018 11:00 AM–12:00 PM

Although ethics topics are widely taught across a multitude of disciplines, very rarely are ethics methods established in that learning process. If the learning stops at ethics topics, there is a disservice as individuals are only equipped to respond to the particular topics to which they have been introduced. A case study will allow attendees, in a team environment, to "walk through" an ethical decision making process to come to a course of action.

(E3): Trolleyology - Responsible Conduct of Research
11 October 2018 01:00 PM–02:00 PM

Highlighting the difference between deontological and consequentialist ethical systems, the historical "trolley problem" will allow a platform for introduction of a specific ethics method. Science, technology, and medicine are driving forces in our society. Like a scientific method is applied when addressing a scientific question, this session aims to teach attendees how to apply an ethics method when addressing an ethical dilemma